Bring a large pot of salted water to a rolling boil over high heat. Add the penne pasta and cook according to package instructions, usually around 10-12 minutes, until al dente. Drain and set aside.

In a large skillet, melt 2 tablespoons of unsalted butter over medium heat. Add the ground beef and break it apart, cooking until browned, about 5-7 minutes.

Stir in 3 minced garlic cloves, salt, pepper, and Italian seasoning. Sauté everything until the garlic is fragrant and golden, about 1-2 minutes.

Fold the drained penne into the skillet with the garlic beef mixture. Add an additional tablespoon of melted butter if desired and stir gently for 2-3 minutes.

Sprinkle 1 cup of shredded cheddar cheese over the penne and stir until melted and gooey. Optionally add grated Parmesan cheese.

Spoon the cheesy penne onto plates and garnish with fresh parsley. Serve immediately.